Frequently Asked Questions
Activated carbon is the standard method for removing chlorine and chloramine from water before it enters a dialysis system, as both compounds can cause serious harm to patients if present in dialysate. GAC beds provide continuous, high-capacity adsorption at the flow rates typical of hemodialysis clinics, and are required as part of water treatment train designs that comply with AAMI and BS EN 23500 standards. Puragen supplies dialysis-grade carbons specifically selected for their purity, adsorption capacity, and low extractables profile.
Dialysis water quality in the US is governed by AAMI standards, which set maximum allowable levels for chemical contaminants, microbial content, and endotoxins in water used for hemodialysis. These standards require that chlorine and chloramine be reduced to non-detectable levels before water contacts the dialyzer membrane. Puragen’s GAC products are selected and documented to support compliance with these requirements.
Exchange frequency depends on the chloramine concentration in the incoming water supply, the flow rate through the carbon bed, and the bed volume specified for the installation. Most dialysis facilities monitor for chloramine breakthrough continuously and schedule carbon exchange based on measured bed exhaustion rather than fixed intervals. Puragen can assist with sizing calculations and exchange scheduling to ensure uninterrupted protection throughout the carbon service life.
Chloramine breakthrough occurs when the carbon bed becomes exhausted and can no longer adsorb incoming chloramine, allowing it to pass into the dialysis water system. Because chloramine cannot be removed by reverse osmosis membranes alone, a failure in the carbon stage poses a direct risk to patient safety. Redundant carbon vessels operated in series, combined with continuous online monitoring, are the standard safeguard against breakthrough events.
Yes. Puragen supports dialysis facilities at all stages, from initial carbon specification and vessel sizing through to scheduled exchange programs and emergency supply. Our integrated logistics network is designed to deliver carbon reliably against the exchange schedules that clinic operations depend on, with full documentation provided for quality and compliance records. Contact Puragen to discuss supply arrangements for your clinic or network of facilities.